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Targeting GPCR-Gβγ-GRK2 signaling as a novel strategy for treating cardiorenal pathologies

The pathologic crosstalk between the heart and kidney is known as cardiorenal syndrome (CRS). While the specific mechanisms underlying this crosstalk remain poorly understood, CRS is associated with exacerbated dysfunction of either or both organs and reduced survival. Maladaptive fibrotic remodelin...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Rudomanova, Valeria, Blaxall, Burns C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466897/
https://ncbi.nlm.nih.gov/pubmed/28130200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.01.020
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