High-Level Acetaldehyde Production in Lactococcus lactis by Metabolic Engineering

Efficient conversion of glucose to acetaldehyde is achieved by nisin-controlled overexpression of Zymomonas mobilis pyruvate decarboxylase (pdc) and Lactococcus lactis NADH oxidase (nox) in L. lactis. In resting cells, almost 50% of the glucose consumed could be redirected towards acetaldehyde by co...

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Hauptverfasser: Bongers, Roger S., Hoefnagel, Marcel H. N., Kleerebezem, Michiel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Physiology and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC546684/
https://ncbi.nlm.nih.gov/pubmed/15691976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.2.1109-1113.2005
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