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Amphiregulin contained in NSCLC-exosomes induces osteoclast differentiation through the activation of EGFR pathway
Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths worldwide. The majority of patients are diagnosed in advanced disease stage. Bone metastasis is the most frequent complication in NSCLC resulting in osteolytic lesions. The perfect balance between bone-resorbing os...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466625/ https://ncbi.nlm.nih.gov/pubmed/28600504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03460-y |
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