Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

Diabetes is a complex metabolic disease that exposes patients to the deleterious effects of hyperglycemia on various organs. Achievement of normoglycemia with exogenous insulin treatment requires the use of high doses of hormone, which increases the risk of life-threatening hypoglycemic episodes. We...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Jaén, Maria Luisa, Vilà, Laia, Elias, Ivet, Jimenez, Veronica, Rodó, Jordi, Maggioni, Luca, Ruiz-de Gopegui, Rafael, Garcia, Miguel, Muñoz, Sergio, Callejas, David, Ayuso, Eduard, Ferré, Tura, Grifoll, Iris, Andaluz, Anna, Ruberte, Jesus, Haurigot, Virginia, Bosch, Fatima
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466581/
https://ncbi.nlm.nih.gov/pubmed/28626777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.03.008
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