Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

Diabetes is a complex metabolic disease that exposes patients to the deleterious effects of hyperglycemia on various organs. Achievement of normoglycemia with exogenous insulin treatment requires the use of high doses of hormone, which increases the risk of life-threatening hypoglycemic episodes. We...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Jaén, Maria Luisa, Vilà, Laia, Elias, Ivet, Jimenez, Veronica, Rodó, Jordi, Maggioni, Luca, Ruiz-de Gopegui, Rafael, Garcia, Miguel, Muñoz, Sergio, Callejas, David, Ayuso, Eduard, Ferré, Tura, Grifoll, Iris, Andaluz, Anna, Ruberte, Jesus, Haurigot, Virginia, Bosch, Fatima
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466581/
https://ncbi.nlm.nih.gov/pubmed/28626777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.03.008
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