Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool

Notch signaling is critical for osteoblastic differentiation; however, the specific contribution of individual Notch ligands is unknown. Parathyroid hormone (PTH) regulates the Notch ligand Jagged1 in osteoblastic cells. To determine if osteolineage Jagged1 contributes to bone homeostasis, selective...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Lawal, Rialnat A, Zhu, Xichao, Batey, Kaylind, Hoffman, Corey M, Georger, Mary A, Radtke, Freddy, Hilton, Matthew J, Xing, Lianping, Frisch, Benjamin J, Calvi, Laura M
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466455/
https://ncbi.nlm.nih.gov/pubmed/28277610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3106
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