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Enforcement of developmental lineage specificity by transcription factor Oct1

Embryonic stem cells co-express Oct4 and Oct1, a related protein with similar DNA-binding specificity. To study the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and inducible-conditional Oct1-deficient ESC lines. ESCs lacking Oct1 show normal appearance, self...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Shen, Zuolian, Kang, Jinsuk, Shakya, Arvind, Tabaka, Marcin, Jarboe, Elke A, Regev, Aviv, Tantin, Dean
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466424/
https://ncbi.nlm.nih.gov/pubmed/28537559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20937
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