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A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress

Oct1 and Oct4 are homologous transcription factors with similar DNA-binding specificities. Here we show that Oct1 is dynamically phosphorylated in vivo following exposure of cells to oxidative and genotoxic stress. We further show that stress regulates the selectivity of both proteins for specific D...

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書誌詳細
主要な著者: Kang, Jinsuk, Gemberling, Matthew, Nakamura, Mitsuhiro, Whitby, Frank G., Handa, Hiroshi, Fairbrother, William G., Tantin, Dean
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2009
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648538/
https://ncbi.nlm.nih.gov/pubmed/19171782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1750709
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