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A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress

Oct1 and Oct4 are homologous transcription factors with similar DNA-binding specificities. Here we show that Oct1 is dynamically phosphorylated in vivo following exposure of cells to oxidative and genotoxic stress. We further show that stress regulates the selectivity of both proteins for specific D...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kang, Jinsuk, Gemberling, Matthew, Nakamura, Mitsuhiro, Whitby, Frank G., Handa, Hiroshi, Fairbrother, William G., Tantin, Dean
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648538/
https://ncbi.nlm.nih.gov/pubmed/19171782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1750709
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