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A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress
Oct1 and Oct4 are homologous transcription factors with similar DNA-binding specificities. Here we show that Oct1 is dynamically phosphorylated in vivo following exposure of cells to oxidative and genotoxic stress. We further show that stress regulates the selectivity of both proteins for specific D...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648538/ https://ncbi.nlm.nih.gov/pubmed/19171782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1750709 |
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