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Combinatorial binding of transcription factors in the pluripotency control regions of the genome

The pluripotency control regions (PluCRs) are defined as genomic regions that are bound by POU5F1, SOX2, and NANOG in vivo. We utilized a high-throughput binding assay to record more than 270,000 different DNA/protein binding measurements along incrementally tiled windows of DNA within these PluCRs....

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Autors principals: Ferraris, Luciana, Stewart, Allan P., Kang, Jinsuk, DeSimone, Alec M., Gemberling, Matthew, Tantin, Dean, Fairbrother, William G.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129248/
https://ncbi.nlm.nih.gov/pubmed/21527551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.115824.110
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