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Amylin Enhances Amyloid-β Peptide Brain to Blood Efflux Across the Blood-Brain Barrier

Findings from Alzheimer’s disease (AD) mouse models showed that amylin treatment improved AD pathology and enhanced amyloid-β (Aβ) brain to blood clearance; however, the mechanism was not investigated. Using the Tg2576 AD mouse model, a single intraperitoneal injection of amylin significantly increa...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Mohamed, Loqman A., Zhu, Haihao, Mousa, Youssef M., Wang, Erming, Qiu, Wei Qiao, Kaddoumi, Amal
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466167/
https://ncbi.nlm.nih.gov/pubmed/28059785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160800
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