Gene-environment interaction in Parkinson’s disease: coffee, ADORA2A, and CYP1A2

BACKGROUND AND PURPOSE: Drinking caffeinated coffee has been reported to protect against Parkinson’s disease (PD). Caffeine is an adenosine A2A receptor (encoded by the gene ADORA2A) antagonist that increases dopaminergic neurotransmission and Cytochrome P450 1A2 (gene: CYP1A2) metabolizes caffeine,...

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Publicat a:Neuroepidemiology
Autors principals: Chuang, Yu-Hsuan, Lill, Christina M., Lee, Pei-Chen, Hansen, Johnni, Lassen, Christina Funch, Bertram, Lars, Greene, Naomi, Sinsheimer, Janet S., Ritz, Beate
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465963/
https://ncbi.nlm.nih.gov/pubmed/28135712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000450855
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