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Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s disease
OBJECTIVE: In MPTP animal models of Parkinson’s disease (PD), caffeine protects neurons by blocking the adenosine receptor A2A (ADORA2A). Caffeine is primarily metabolized by cytochrome P450 1A2 (CYP1A2). Our objective was to examine whether ADORA2A and CYP1A2 polymorphisms are associated with PD ri...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556904/ https://ncbi.nlm.nih.gov/pubmed/21281405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1468-1331.2011.03353.x |
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