Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s disease

OBJECTIVE: In MPTP animal models of Parkinson’s disease (PD), caffeine protects neurons by blocking the adenosine receptor A2A (ADORA2A). Caffeine is primarily metabolized by cytochrome P450 1A2 (CYP1A2). Our objective was to examine whether ADORA2A and CYP1A2 polymorphisms are associated with PD ri...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Popat, R.A., Van Den Eeden, S.K., Tanner, C.M., Kamel, F., Umbach, D. M., Marder, K., Mayeux, R., Ritz, B., Ross, G. Webster, Petrovitch, H., Topol, B., McGuire, V., Costello, Sadie, Manthripragada, Angelika.D., Southwick, A., Myers, R.M., Nelson, L. M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556904/
https://ncbi.nlm.nih.gov/pubmed/21281405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1468-1331.2011.03353.x
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares