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Gene-environment interaction in Parkinson’s disease: coffee, ADORA2A, and CYP1A2
BACKGROUND AND PURPOSE: Drinking caffeinated coffee has been reported to protect against Parkinson’s disease (PD). Caffeine is an adenosine A2A receptor (encoded by the gene ADORA2A) antagonist that increases dopaminergic neurotransmission and Cytochrome P450 1A2 (gene: CYP1A2) metabolizes caffeine,...
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| 出版年: | Neuroepidemiology |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5465963/ https://ncbi.nlm.nih.gov/pubmed/28135712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000450855 |
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