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Gene-environment interaction in Parkinson’s disease: coffee, ADORA2A, and CYP1A2

BACKGROUND AND PURPOSE: Drinking caffeinated coffee has been reported to protect against Parkinson’s disease (PD). Caffeine is an adenosine A2A receptor (encoded by the gene ADORA2A) antagonist that increases dopaminergic neurotransmission and Cytochrome P450 1A2 (gene: CYP1A2) metabolizes caffeine,...

詳細記述

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書誌詳細
出版年:Neuroepidemiology
主要な著者: Chuang, Yu-Hsuan, Lill, Christina M., Lee, Pei-Chen, Hansen, Johnni, Lassen, Christina Funch, Bertram, Lars, Greene, Naomi, Sinsheimer, Janet S., Ritz, Beate
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465963/
https://ncbi.nlm.nih.gov/pubmed/28135712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000450855
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