Involvement of the Interferon-Regulated Antiviral Proteins PKR and RNase L in Reovirus-Induced Shutoff of Cellular Translation

Cellular translation is inhibited following infection with most strains of reovirus, but the mechanisms responsible for this phenomenon remain to be elucidated. The extent of host shutoff varies in a strain-dependent manner; infection with the majority of strains leads to strong host shutoff, while...

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Detalhes bibliográficos
Main Authors: Smith, Jennifer A., Schmechel, Stephen C., Williams, Bryan R. G., Silverman, Robert H., Schiff, Leslie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546589/
https://ncbi.nlm.nih.gov/pubmed/15681426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2240-2250.2005
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