Human Cytomegalovirus Genes in the 15-Kilobase Region Are Required for Viral Replication in Implanted Human Tissues in SCID Mice

Since animal models for studying human cytomegalovirus (HCMV) replication in vivo and pathogenesis are not available, severe combined immunodeficiency mice into which human tissues were implanted (SCID-hu mice) provide an alternative and valuable model for such studies. The HCMV clinical isolates, i...

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Autori principali: Wang, Weijia, Taylor, Shannon L., Leisenfelder, Stacey A., Morton, Robert, Moffat, Jennifer F., Smirnov, Sergey, Zhu, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC546580/
https://ncbi.nlm.nih.gov/pubmed/15681414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2115-2123.2005
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