Formulation with CpG Oligodeoxynucleotides Prevents Induction of Pulmonary Immunopathology following Priming with Formalin-Inactivated or Commercial Killed Bovine Respiratory Syncytial Virus Vaccine

Commercial killed bovine respiratory syncytial virus (K-BRSV) and formalin-inactivated BRSV (FI-BRSV) tend to induce Th2-type immune responses, which may not be protective and may even be detrimental during subsequent exposure to the virus. In this study we assessed the ability of CpG oligodeoxynucl...

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Autors principals: Oumouna, M., Mapletoft, J. W., Karvonen, B. C., Babiuk, L. A., van Drunen Littel-van den Hurk, S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC546558/
https://ncbi.nlm.nih.gov/pubmed/15681404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2024-2032.2005
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