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An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure

Aggregation of specific proteins in the brains of patients with chronic mental illness as a result of disruptions in proteostasis is an emerging theme in the study of schizophrenia in particular. Proteins including DISC1 (disrupted in schizophrenia 1) and dysbindin-1B are found in insoluble forms wi...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Bradshaw, Nicholas J., Yerabham, Antony S. K., Marreiros, Rita, Zhang, Tao, Nagel-Steger, Luitgard, Korth, Carsten
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465484/
https://ncbi.nlm.nih.gov/pubmed/28438837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767939
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