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The TRIOBP Isoforms and Their Distinct Roles in Actin Stabilization, Deafness, Mental Illness, and Cancer

The TRIOBP (TRIO and F-actin Binding Protein) gene encodes multiple proteins, which together play crucial roles in modulating the assembly of the actin cytoskeleton. Splicing of the TRIOBP gene is complex, with the two most studied TRIOBP protein isoforms sharing no overlapping amino acid sequence w...

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Bibliographic Details
Published in:Molecules
Main Authors: Zaharija, Beti, Samardžija, Bobana, Bradshaw, Nicholas J.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663296/
https://ncbi.nlm.nih.gov/pubmed/33121024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25214967
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