Norovirus Proteinase-Polymerase and Polymerase Are Both Active Forms of RNA-Dependent RNA Polymerase

In vitro mapping studies of the MD145 norovirus (Caliciviridae) ORF1 polyprotein identified two stable cleavage products containing the viral RNA-dependent RNA polymerase (RdRp) domains: ProPol (a precursor comprised of both the proteinase and polymerase) and Pol (the mature polymerase). The goal of...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Belliot, Gaël, Sosnovtsev, Stanislav V., Chang, Kyeong-Ok, Babu, Vijay, Uche, Uzo, Arnold, Jamie J., Cameron, Craig E., Green, Kim Y.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2005
Assuntos:	Replication
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15681440/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.4.2393-2403.2005
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