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Mutagenesis of Tyrosine 24 in the VPg Protein Is Lethal for Feline Calicivirus

The genome of feline calicivirus (FCV) is an ∼7.7-kb single-stranded positive-sense RNA molecule that is polyadenylated at its 3′ end and covalently linked to a VPg protein (calculated mass, 12.6 kDa) at its 5′ end. We performed a mutational analysis of the VPg protein in order to identify amino aci...

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Detalhes bibliográficos
Main Authors: Mitra, Tanaji, Sosnovtsev, Stanislav V., Green, Kim Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387666/
https://ncbi.nlm.nih.gov/pubmed/15078978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4931-4935.2004
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