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Norovirus Proteinase-Polymerase and Polymerase Are Both Active Forms of RNA-Dependent RNA Polymerase

In vitro mapping studies of the MD145 norovirus (Caliciviridae) ORF1 polyprotein identified two stable cleavage products containing the viral RNA-dependent RNA polymerase (RdRp) domains: ProPol (a precursor comprised of both the proteinase and polymerase) and Pol (the mature polymerase). The goal of...

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Detalhes bibliográficos
Main Authors: Belliot, Gaël, Sosnovtsev, Stanislav V., Chang, Kyeong-Ok, Babu, Vijay, Uche, Uzo, Arnold, Jamie J., Cameron, Craig E., Green, Kim Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546540/
https://ncbi.nlm.nih.gov/pubmed/15681440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2393-2403.2005
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