A Combination of Podophyllotoxin and Rutin Alleviates Radiation-Induced Pneumonitis and Fibrosis through Modulation of Lung Inflammation in Mice

Pneumonitis and pulmonary fibrosis are predominant consequences of radiation exposure, whether planned or accidental. The present study, demonstrates radioprotective potential of a formulation, prepared by combining podophyllotoxin and rutin (G-003M), in mice exposed to 11 Gy thoracic gamma radiatio...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Verma, Savita, Kalita, Bhargab, Bajaj, Sania, Prakash, Hridayesh, Singh, Ajay Kumar, Gupta, Manju Lata
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465247/
https://ncbi.nlm.nih.gov/pubmed/28649248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00658
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