Podophyllotoxin and Rutin Modulates Ionizing Radiation-Induced Oxidative Stress and Apoptotic Cell Death in Mice Bone Marrow and Spleen

The present study is aimed to investigate the radioprotective efficacy of G-003M (combination of podophyllotoxin and rutin) against gamma radiation-induced oxidative stress and subsequent cell death in mice bone marrow and spleen. Prophylactic administration of G-003M (−1 h) rendered more than 85% s...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Singh, Abhinav, Yashavarddhan, M. H., Kalita, Bhargab, Ranjan, Rajiv, Bajaj, Sania, Prakash, Hridayesh, Gupta, Manju Lata
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326804/
https://ncbi.nlm.nih.gov/pubmed/28289414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00183
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