A Combination of Podophyllotoxin and Rutin Alleviates Radiation-Induced Pneumonitis and Fibrosis through Modulation of Lung Inflammation in Mice

Pneumonitis and pulmonary fibrosis are predominant consequences of radiation exposure, whether planned or accidental. The present study, demonstrates radioprotective potential of a formulation, prepared by combining podophyllotoxin and rutin (G-003M), in mice exposed to 11 Gy thoracic gamma radiatio...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Verma, Savita, Kalita, Bhargab, Bajaj, Sania, Prakash, Hridayesh, Singh, Ajay Kumar, Gupta, Manju Lata
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465247/
https://ncbi.nlm.nih.gov/pubmed/28649248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00658
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