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Considerations of Protein Subpockets in Fragment-Based Drug Design

While the fragment-based drug design approach continues to gain importance, gaps in the tools and methods available in the identification and accurate utilization of protein subpockets have limited the scope. The importance of these features of small molecule–protein recognition is highlighted with...

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Detalhes bibliográficos
Publicado no:Chem Biol Drug Des
Main Authors: Bartolowits, Matthew, Davisson, V. Jo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464946/
https://ncbi.nlm.nih.gov/pubmed/26307335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12631
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