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Considerations of Protein Subpockets in Fragment-Based Drug Design

While the fragment-based drug design approach continues to gain importance, gaps in the tools and methods available in the identification and accurate utilization of protein subpockets have limited the scope. The importance of these features of small molecule–protein recognition is highlighted with...

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Publicat a:Chem Biol Drug Des
Autors principals: Bartolowits, Matthew, Davisson, V. Jo
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464946/
https://ncbi.nlm.nih.gov/pubmed/26307335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12631
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