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Evolutions in fragment-based drug design: the deconstruction–reconstruction approach
Recent advances in the understanding of molecular recognition and protein–ligand interactions have facilitated rapid development of potent and selective ligands for therapeutically relevant targets. Over the past two decades, a variety of useful approaches and emerging techniques have been developed...
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| Publicado no: | Drug Discov Today |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4305461/ https://ncbi.nlm.nih.gov/pubmed/25263697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.09.015 |
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