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Evolutions in fragment-based drug design: the deconstruction–reconstruction approach

Recent advances in the understanding of molecular recognition and protein–ligand interactions have facilitated rapid development of potent and selective ligands for therapeutically relevant targets. Over the past two decades, a variety of useful approaches and emerging techniques have been developed...

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Bibliografski detalji
Izdano u:Drug Discov Today
Glavni autori: Chen, Haijun, Zhou, Xiaobin, Wang, Ailan, Zheng, Yunquan, Gao, Yu, Zhou, Jia
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305461/
https://ncbi.nlm.nih.gov/pubmed/25263697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.09.015
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