Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy

BACKGROUND. Molecular profiling is revolutionizing cancer diagnostics and leading to personalized therapeutic approaches. Herein we describe our clinical experience performing targeted sequencing for 31 pediatric neuro-oncology patients. METHODS. We sequenced 510 cancer-associated genes from tumor a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Kline, Cassie N., Joseph, Nancy M., Grenert, James P., van Ziffle, Jessica, Talevich, Eric, Onodera, Courtney, Aboian, Mariam, Cha, Soonmee, Raleigh, David R., Braunstein, Steve, Torkildson, Joseph, Samuel, David, Bloomer, Michelle, Campomanes, Alejandra G. de Alba, Banerjee, Anuradha, Butowski, Nicholas, Raffel, Corey, Tihan, Tarik, Bollen, Andrew W., Phillips, Joanna J., Korn, W. Michael, Yeh, Iwei, Bastian, Boris C., Gupta, Nalin, Mueller, Sabine, Perry, Arie, Nicolaides, Theodore, Solomon, David A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2017
נושאים:
Pediatric Neuro-Oncology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464451/
https://ncbi.nlm.nih.gov/pubmed/28453743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now254
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים