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Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models
BACKGROUND. Molecular profile of glioblastoma multiforme (GBM) revealed 4 subtypes, 2 of which, proneural and mesenchymal, have been predominantly observed, with the latter displaying a more aggressive phenotype and increased therapeutic resistance. Single-cell RNA sequencing revealed that multiple...
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| Vydáno v: | Neuro Oncol |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464448/ https://ncbi.nlm.nih.gov/pubmed/28062830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now253 |
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