Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Synucleinopathies are a group of neurodegenerative disorders sharing the common feature of misfolding and accumulation of the presynaptic protein α‐synuclein (α‐syn) into insoluble aggregates. Within this diverse group, Dementia with Lewy Bodies (DLB) is characterized by the aberrant accumulation of...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Goldberg, Natalie R.S., Marsh, Samuel E., Ochaba, Joseph, Shelley, Brandon C., Davtyan, Hayk, Thompson, Leslie M., Steffan, Joan S., Svendsen, Clive N., Blurton‐Jones, Mathew
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Translational Research Articles and Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464354/
https://ncbi.nlm.nih.gov/pubmed/28225193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.16-0362
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