Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization.

Lignende værker

• Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover.
  af: Dauvois, S, et al.
  Udgivet: (1992)
• ICI 164,384: a control for investigating estrogen responsive genes.
  af: Bondy, K L, et al.
  Udgivet: (1993)
• An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor.
  af: Arnold, S F, et al.
  Udgivet: (1995)
• The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules
  af: Oliveira, Cleida A, et al.
  Udgivet: (2003)
• Activation of the human estrogen receptor by the antiestrogens ICI 182,780 and tamoxifen in yeast genetic systems: Implications for their mechanism of action
  af: Dudley, Mark W., et al.
  Udgivet: (2000)