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Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide

BACKGROUND. Optimal adjuvant management of adult low-grade gliomas is controversial. Recently described tumor classification based on molecular subtype has the potential to individualize adjuvant therapy but has not yet been evaluated as part of a prospective trial. METHODS. Patients aged 18 or olde...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wahl, Michael, Phillips, Joanna J., Molinaro, Annette M., Lin, Yi, Perry, Arie, Haas-Kogan, Daphne A., Costello, Joseph F., Dayal, Manisha, Butowski, Nicholas, Clarke, Jennifer L., Prados, Michael, Nelson, Sarah, Berger, Mitchel S., Chang, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464133/
https://ncbi.nlm.nih.gov/pubmed/27571885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now176
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