OS09.4 Identification of a novel H3.3.K27M mutation-derived neoantigen epitope and cloning of H3.3.K27M-specific T-cell receptor for T-cell therapy in gliomas

Brain cancers are the leading cause of cancer related mortality and morbidity in children and young adults. Children with diffuse intrinsic brainstem malignant gliomas have one-year progression-free survival rates below 25% and median overall survival of 9 to 10 months with current treatment options...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Chheda, Z., Kohanbash, G., Sidney, J., Okada, K., Jahan, N., Mueller, S., Sette, A., Hou, Y., Okada, H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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ORAL PRESENTATIONS
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463716/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.063
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