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OS01.5 Development of TERT-targeting therapy using eribulin mesylate in mouse glioblastoma model
Introduction: Despite of recent extensive genome analysis, no effective molecular targeting therapy has been successfully developed in patients with glioblastomas (GBMs). Approximately 60–80% of GBM harbour mutations in the promoter region of telomerase reverse transcriptase (TERT) that leads to upr...
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| Опубликовано в: : | Neuro Oncol |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463620/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.004 |
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