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P08.41 Development of a novel TERT-targeting therapy for glioblastomas
INTRODUCTION: Approximately 60–80% of GBM harbour mutations in the promoter region of TERT that leads to its upregulation, making it the most common single genetic abnormalities in GBM. TERT, a reverse-transcriptase subunit of telomerase, has been an attractive candidate for therapy target because o...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782670/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.174 |
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