Rapamycin efficiently promotes cardiac differentiation of mouse embryonic stem cells

To investigate the effects of rapamycin on cardiac differentiation, murine embryonic stem cells (ESCs) were induced into cardiomyocytes by 10(−4) M ascorbic acid (AA), 20 nM rapamycin alone or 0.01% solvent DMSO. We found that rapamycin alone was insufficient to initiate cardiomyogenesis. Then, the...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Lu, Qin, Liu, Yinan, Wang, Yang, Wang, Weiping, Yang, Zhe, Li, Tao, Tian, Yuyao, Chen, Ping, Ma, Kangtao, Jia, Zhuqing, Zhou, Chunyan
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463265/
https://ncbi.nlm.nih.gov/pubmed/28396518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160552
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