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Rapamycin efficiently promotes cardiac differentiation of mouse embryonic stem cells
To investigate the effects of rapamycin on cardiac differentiation, murine embryonic stem cells (ESCs) were induced into cardiomyocytes by 10(−4) M ascorbic acid (AA), 20 nM rapamycin alone or 0.01% solvent DMSO. We found that rapamycin alone was insufficient to initiate cardiomyogenesis. Then, the...
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| Veröffentlicht in: | Biosci Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463265/ https://ncbi.nlm.nih.gov/pubmed/28396518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160552 |
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