MiR-499 Regulates Cell Proliferation and Apoptosis during Late-Stage Cardiac Differentiation via Sox6 and Cyclin D1

BACKGROUND: MiR-499 is a cardiac-abundant miRNA. However, the biological functions of miR-499 in differentiated cardiomyocytes or in the cardiomyocyte differentiation process is not very clear. Sox6 is believed to be one of its targets, and is also believed to play a role in cardiac differentiation....

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Main Authors: Li, Xianhui, Wang, Jiaji, Jia, Zhuqing, Cui, Qinghua, Zhang, Chenguang, Wang, Weiping, Chen, Ping, Ma, Kangtao, Zhou, Chunyan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770584/
https://ncbi.nlm.nih.gov/pubmed/24040263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074504
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