SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition

Sepsis-induced cardiac apoptosis is one of the major pathogenic factors in myocardial dysfunction. As it enhances numerous proinflammatory factors, lipopolysaccharide (LPS) is considered the principal mediator in this pathological process. However, the detailed mechanisms involved are unclear. In th...

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Bibliografske podrobnosti
izdano v:Apoptosis
Main Authors: Jia, Zhuqing, Wang, Jiaji, Shi, Qiong, Liu, Siyu, Wang, Weiping, Tian, Yuyao, Lu, Qin, Chen, Ping, Ma, Kangtao, Zhou, Chunyan
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2015
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712245/
https://ncbi.nlm.nih.gov/pubmed/26659076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1201-6
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