SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition

Sepsis-induced cardiac apoptosis is one of the major pathogenic factors in myocardial dysfunction. As it enhances numerous proinflammatory factors, lipopolysaccharide (LPS) is considered the principal mediator in this pathological process. However, the detailed mechanisms involved are unclear. In th...

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Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: Jia, Zhuqing, Wang, Jiaji, Shi, Qiong, Liu, Siyu, Wang, Weiping, Tian, Yuyao, Lu, Qin, Chen, Ping, Ma, Kangtao, Zhou, Chunyan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712245/
https://ncbi.nlm.nih.gov/pubmed/26659076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1201-6
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