SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition

Sepsis-induced cardiac apoptosis is one of the major pathogenic factors in myocardial dysfunction. As it enhances numerous proinflammatory factors, lipopolysaccharide (LPS) is considered the principal mediator in this pathological process. However, the detailed mechanisms involved are unclear. In th...

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Detalles Bibliográficos
Publicado en:Apoptosis
Main Authors: Jia, Zhuqing, Wang, Jiaji, Shi, Qiong, Liu, Siyu, Wang, Weiping, Tian, Yuyao, Lu, Qin, Chen, Ping, Ma, Kangtao, Zhou, Chunyan
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2015
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712245/
https://ncbi.nlm.nih.gov/pubmed/26659076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1201-6
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