Tacrolimus Updated Guidelines through popPK Modeling: How to Benefit More from CYP3A Pre-emptive Genotyping Prior to Kidney Transplantation

Tacrolimus (Tac) is a profoundly effective immunosuppressant that reduces the risk of rejection after solid organ transplantation. However, its use is hampered by its narrow therapeutic window along with its highly variable pharmacological (pharmacokinetic [PK] and pharmacodynamic [PD]) profile. Par...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Woillard, Jean-Baptiste, Mourad, Michel, Neely, Michael, Capron, Arnaud, van Schaik, Ron H., van Gelder, Teun, Lloberas, Nuria, Hesselink, Dennis A., Marquet, Pierre, Haufroid, Vincent, Elens, Laure
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462973/
https://ncbi.nlm.nih.gov/pubmed/28642710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00358
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia