Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia

The causes of individual relapses in children with acute lymphoblastic leukemia (ALL) remain incompletely understood. We evaluated the contribution of germline genetic factors to relapse in 2,225 children treated on Children’s Oncology Group trial AALL0232. We identified 302 germline single nucleoti...

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Publié dans:Leukemia
Auteurs principaux: Karol, Seth E., Larsen, Eric, Cheng, Cheng, Cao, Xueyuan, Yang, Wenjian, Ramsey, Laura B., Fernandez, Christian A., McCorkle, Joseph R., Paugh, Steven W., Autry, Robert J., Lopez-Lopez, Elixabet, Diouf, Barthelemy, Jeha, Sima, Pui, Ching-Hon, Raetz, Elizabeth A., Winick, Naomi J., Carroll, William L., Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi, Evans, William E., Yang, Jun J., Relling, Mary V.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462853/
https://ncbi.nlm.nih.gov/pubmed/28096535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.24
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