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Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
Colorectal cancer (CRC) is a leading cause of death, yet facile preclinical models that mimic the natural stages of CRC progression are lacking. Through the orthotopic engraftment of colon organoids we describe a broadly usable immunocompetent CRC model that recapitulates the entire adenoma-adenocar...
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| 出版年: | Nat Biotechnol |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462850/ https://ncbi.nlm.nih.gov/pubmed/28459450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3837 |
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