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Co-targeting cancer stem-like cells and bulk cancer cells with a bispecific antibody
Epidermal growth factor receptor (EGFR) is a widely recognized target for tumors, but resistance is commonly reported. Recently, we reported that dual targeting of EGFR and NOTCH2/3 receptors with antibody CT16 showed a strong anti-stem effect both in vitro and in vivo to overcome resistance of EGFR...
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| Udgivet i: | Mol Cell Oncol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462514/ https://ncbi.nlm.nih.gov/pubmed/28616585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1308851 |
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