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Rare disease models provide insight into inherited forms of neurodegeneration

Hereditary spastic paraplegias (HSPs) are a group of inherited neurodegenerative conditions characterised by retrograde degeneration of the longest motor neurons in the corticospinal tract, resulting in muscle weakness and spasticity of the lower limbs. To date more than 70 genetic loci have been as...

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Bibliografske podrobnosti
izdano v:J Rare Dis Res Treat
Main Authors: Fowler, Philippa C., Byrne, Dwayne J., O’Sullivan, Niamh C.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462091/
https://ncbi.nlm.nih.gov/pubmed/28603788
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