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Rare disease models provide insight into inherited forms of neurodegeneration

Hereditary spastic paraplegias (HSPs) are a group of inherited neurodegenerative conditions characterised by retrograde degeneration of the longest motor neurons in the corticospinal tract, resulting in muscle weakness and spasticity of the lower limbs. To date more than 70 genetic loci have been as...

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Detalhes bibliográficos
Publicado no:J Rare Dis Res Treat
Main Authors: Fowler, Philippa C., Byrne, Dwayne J., O’Sullivan, Niamh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462091/
https://ncbi.nlm.nih.gov/pubmed/28603788
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