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Deficiency in DNA damage response, a new characteristic of cells infected with latent HIV-1

Viruses can interact with host cell molecules responsible for the recognition and repair of DNA lesions, resulting in dysfunctional DNA damage response (DDR). Cells with inefficient DDR are more vulnerable to therapeutic approaches that target DDR, thereby raising DNA damage to a threshold that trig...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Piekna-Przybylska, Dorota, Sharma, Gaurav, Maggirwar, Sanjay B., Bambara, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462075/
https://ncbi.nlm.nih.gov/pubmed/28388353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1312225
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