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U3 Region in the HIV-1 Genome Adopts a G-Quadruplex Structure in Its RNA and DNA Sequence

[Image: see text] Genomic regions rich in G residues are prone to adopt G-quadruplex structure. Multiple Sp1-binding motifs arranged in tandem have been suggested to form this structure in promoters of cancer-related genes. Here, we demonstrate that the G-rich proviral DNA sequence of the HIV-1 U3 r...

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Detalhes bibliográficos
Main Authors: Piekna-Przybylska, Dorota, Sullivan, Mark A., Sharma, Gaurav, Bambara, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007979/
https://ncbi.nlm.nih.gov/pubmed/24735378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4016692
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