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Mechanism of HIV-1 RNA Dimerization in the Central Region of the Genome and Significance for Viral Evolution

The genome of HIV-1 consists of two identical or nearly identical RNA molecules. The RNA genomes are held in the same, parallel orientation by interactions at the dimer initiation site (DIS). Previous studies showed that in addition to interactions at DIS, sequences located 100 nucleotides downstrea...

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Detalhes bibliográficos
Main Authors: Piekna-Przybylska, Dorota, Sharma, Gaurav, Bambara, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745356/
https://ncbi.nlm.nih.gov/pubmed/23839990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477265
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