Nitric oxide prevents a pathogen permissive granulocytic inflammation during tuberculosis

Nitric oxide (NO) contributes to protection from tuberculosis (TB). It is generally assumed that this protection is due to direct inhibition of Mycobacterium tuberculosis (Mtb) growth, which prevents subsequent pathological inflammation. In contrast, we report NO primarily protects mice by repressin...

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Bibliographic Details
Published in:Nat Microbiol
Main Authors: Mishra, Bibhuti B., Lovewell, Rustin R., Olive, Andrew J, Zhang, Guoliang, Wang, Wenfei, Eugenin, Eliseo, Smith, Clare M, Yao, Jia Phuah, Long, Jarukit E, Dubuke, Michelle L, Palace, Samantha G., Goguen, Jon D., Baker, Richard E., Nambi, Subhalaxmi, Mishra, Rabinarayan, Booty, Matthew G, Baer, Christina E., Shaffer, Scott A, Dartois, Veronique, McCormick, Beth, Chen, Xinchun, Sassetti, Christopher M.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461879/
https://ncbi.nlm.nih.gov/pubmed/28504669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.72
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