Fine-tuning of Substrate Affinity Leads to Alternative Roles of Mycobacterium tuberculosis Fe(2+)-ATPases

Little is known about iron efflux transporters within bacterial systems. Recently, the participation of Bacillus subtilis PfeT, a P(1B4)-ATPase, in cytoplasmic Fe(2+) efflux has been proposed. We report here the distinct roles of mycobacterial P(1B4)-ATPases in the homeostasis of Co(2+) and Fe(2+)....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Patel, Sarju J., Lewis, Brianne E., Long, Jarukit E., Nambi, Subhalaxmi, Sassetti, Christopher M., Stemmler, Timothy L., Argüello, José M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Membrane Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882424/
https://ncbi.nlm.nih.gov/pubmed/27022029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.718239
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