Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor–Related Protein 6

Connective tissue growth factor (CTGF), a matrix-associated protein with four distinct cytokine binding domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated in fibroblasts and myofibroblasts in disease. Here, we investigated the role of CTGF in fibrogeni...

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Bibliografiska uppgifter
I publikationen:J Am Soc Nephrol
Huvudupphovsmän: Johnson, Bryce G., Ren, Shuyu, Karaca, Gamze, Gomez, Ivan G., Fligny, Cécile, Smith, Benjamin, Ergun, Ayla, Locke, George, Gao, Benbo, Hayes, Sebastian, MacDonnell, Scott, Duffield, Jeremy S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2017
Ämnen:
Basic Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461793/
https://ncbi.nlm.nih.gov/pubmed/28130402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080826
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